Population genetics interactive widget showing how random genetic drift affects allele frequencies in populations of different sizes

A single generation can erase genes

When a small group founds a new population, rare alleles can vanish or surge to dominance purely by chance—no selection required. Watch how population size determines whether genetic diversity survives random drift across generations.

Gene Pool Simulation
Generation 1
Drag to change founding population size
30 Founders · 2 Alleles Active
Founding Population Size
10 50 100 200
Allele A Frequency
50%
Diversity Index
1.00

A population bottleneck occurs when a large population suddenly crashes—disease, natural disaster, or habitat loss—leaving only a small number of survivors to rebuild. The surviving group carries only a fraction of the original genetic diversity, and rare alleles are often lost forever. Even if the population later rebounds to millions, it can never recover the genetic variants that disappeared in the bottleneck. This happened to cheetahs around 10,000 years ago: today every cheetah is so genetically similar they can accept skin grafts from unrelated individuals, making the entire species vulnerable to the same diseases.

Know This

Small populations lose rare alleles to random drift faster than selection can preserve them, which is why founder effects and bottlenecks permanently reduce genetic diversity regardless of later population growth.